diff --git a/pymisp/api.py b/pymisp/api.py
index ae96745..784c43e 100644
--- a/pymisp/api.py
+++ b/pymisp/api.py
@@ -28,6 +28,17 @@ from .mispevent import MISPEvent, MISPAttribute, MISPSighting, MISPLog, MISPObje
     MISPGalaxyCluster, MISPGalaxyClusterRelation, MISPCorrelationExclusion
 from .abstract import pymisp_json_default, MISPTag, AbstractMISP, describe_types
 
+
+# Enable TCP keepalive by default on every requests
+import socket
+from urllib3.connection import HTTPConnection
+HTTPConnection.default_socket_options = HTTPConnection.default_socket_options + [
+    (socket.SOL_SOCKET, socket.SO_KEEPALIVE, 1),  # enable keepalive
+    (socket.SOL_TCP, socket.TCP_KEEPIDLE, 30),  # Start pinging after 30s of idle time
+    (socket.SOL_TCP, socket.TCP_KEEPINTVL, 10),  # ping every 10s
+    (socket.SOL_TCP, socket.TCP_KEEPCNT, 6)  # kill the connection if 6 ping fail  (60s total)
+]
+
 try:
     # cached_property exists since Python 3.8
     from functools import cached_property  # type: ignore