{ "namespace": "doping-substances", "description": "This taxonomy aims to list doping substances", "version": 2, "expanded": "Doping substances", "predicates": [ { "value": "anabolic agents", "description": "Anabolic agents are prohibited." }, { "value": "peptide hormones, growth factors, related substances and mimetics", "description": "The following substances, and other substances with similar chemical structure or similar biological effect(s), are prohibited." }, { "value": "beta-2 agonists", "description": "All selective and non-selective beta-2 agonists, including all optical isomers, are prohibited." }, { "value": "hormone and metabolic modulators", "description": "The following hormone and metabolic modulators are prohibited." }, { "value": "diuretics and masking agents", "description": "All diuretics and masking agents, including all optical isomers, e.g. d- and l- where relevant, are prohibited." }, { "value": "manipulation of blood and blood components", "description": "The following are prohibited" }, { "value": "chemical and physical manipulation", "description": "The following are prohibited" }, { "value": "gene and cell doping", "description": "The following, with the potential to enhance sport performance, are prohibited" }, { "value": "stimulants", "description": "Substances of Abuse in this section: cocaine and methylenedioxymethamphetamine (MDMA / “ecstasy”)." }, { "value": "narcotics", "description": "The following narcotics, including all optical isomers, e.g. d- and l- where relevant, are prohibited." }, { "value": "cannabinoids" }, { "value": "glucocorticoids", "description": "All glucocorticoids are prohibited when administered by any injectable, oral [including oromucosal (e.g. buccal, gingival, sublingual)] or rectal route." }, { "value": "beta-blockers", "description": "Beta-blockers are prohibited In-Competition only, in the following sports, and also prohibited Out-of-Competition where indicated (*)." } ], "values": [ { "predicate": "anabolic agents", "entry": [ { "value": "1-androstenediol", "expanded": "1-androstenediol (5α-androst-1-ene-3β, 17β-diol)" }, { "value": "1-androstenedione", "expanded": "1-androstenedione (5α-androst-1-ene-3, 17-dione)" }, { "value": "1-androsterone", "expanded": "1-androsterone (3α-hydroxy-5α-androst-1-ene-17-one)" }, { "value": "1-epiandrosterone", "expanded": "1-epiandrosterone (3β-hydroxy-5α-androst-1-ene-17-one)" }, { "value": "1-testosterone", "expanded": "1-testosterone (17β-hydroxy-5α-androst-1-en-3-one)" }, { "value": "4-androstenediol", "expanded": "4-androstenediol (androst-4-ene-3β,17β-diol)" }, { "value": "4-hydroxytestosterone", "expanded": "4-hydroxytestosterone (4,17β-dihydroxyandrost-4-en-3-one)" }, { "value": "5-androstenedione", "expanded": "5-androstenedione (androst-5-ene-3,17-dione)" }, { "value": "7α-hydroxy-dhea" }, { "value": "7β-hydroxy-dhea" }, { "value": "7-keto-dhea" }, { "value": "17α-methylepithiostanol", "expanded": "17α-methylepithiostanol (epistane)" }, { "value": "19-norandrostenediol", "expanded": "19-norandrostenediol  (estr-4-ene-3,17-diol)" }, { "value": "19-norandrostenedione", "expanded": "19-norandrostenedione (estr-4-ene-3,17-dione)" }, { "value": "androst-4-ene-3,11,17-trione", "expanded": "androst-4-ene-3,11,17-trione (11-ketoandrostenedione, adrenosterone)" }, { "value": "androstanolone", "expanded": "androstanolone (5α-dihydrotestosterone, 17β-hydroxy-5α-androstan-3-one)" }, { "value": "androstenediol", "expanded": "androstenediol (androst-5-ene-3β,17β-diol)" }, { "value": "androstenedione", "expanded": "androstenedione (androst-4-ene-3,17-dione)" }, { "value": "bolasterone" }, { "value": "boldenone" }, { "value": "boldione", "expanded": "boldione (androsta-1,4-diene-3,17-dione)" }, { "value": "calusterone" }, { "value": "clostebol" }, { "value": "danazol", "expanded": "danazol ([1,2]oxazolo[4’,5’:2,3]pregna-4-en-20-yn-17α-ol)" }, { "value": "dehydrochlormethyltestosterone", "expanded": "dehydrochlormethyltestosterone (4-chloro-17β-hydroxy-17α-methylandrosta-1,4-dien-3-one)" }, { "value": "desoxymethyltestosterone", "expanded": "desoxymethyltestosterone (17α-methyl-5α-androst-2-en-17β-ol and 17α-methyl-5α-androst-3-en-17β-ol)" }, { "value": "drostanolone" }, { "value": "epiandrosterone", "expanded": "epiandrosterone (3β-hydroxy-5α-androstan-17-one)" }, { "value": "epi-dihydrotestosterone", "expanded": "epi-dihydrotestosterone (17β-hydroxy-5β-androstan-3-one)" }, { "value": "epitestosterone" }, { "value": "ethylestrenol", "expanded": "ethylestrenol  (19-norpregna-4-en-17α-ol)" }, { "value": "fluoxymesterone" }, { "value": "formebolone" }, { "value": "furazabol", "expanded": "furazabol (17α-methyl [1,2,5] oxadiazolo[3’,4’:2,3]-5α-androstan-17β-ol)" }, { "value": "gestrinone" }, { "value": "mestanolone" }, { "value": "mesterolone" }, { "value": "metandienone", "expanded": "metandienone (17β-hydroxy-17α- methylandrosta-1,4-dien-3-one)" }, { "value": "metenolone" }, { "value": "methandriol" }, { "value": "methasterone", "expanded": "methasterone (17β-hydroxy-2α,17α- dimethyl-5α-androstan-3-one)" }, { "value": "methyl-1-testosterone", "expanded": "methyl-1-testosterone (17β-hydroxy-17α- methyl-5α-androst-1-en-3-one)" }, { "value": "methylclostebol" }, { "value": "methyldienolone", "expanded": "methyldienolone (17β-hydroxy-17α- methylestra-4,9-dien-3-one)" }, { "value": "methylnortestosterone", "expanded": "methylnortestosterone (17β-hydroxy-17α- methylestr-4-en-3-one)" }, { "value": "methyltestosterone" }, { "value": "metribolone", "expanded": "metribolone (methyltrienolone, 17β-hydroxy- 17α-methylestra-4,9,11-trien-3-one)" }, { "value": "mibolerone" }, { "value": "nandrolone", "expanded": "nandrolone (19-nortestosterone)" }, { "value": "norboletone" }, { "value": "norclostebol", "expanded": "norclostebol (4-chloro-17β-ol-estr-4-en-3- one)" }, { "value": "norethandrolone" }, { "value": "oxabolone" }, { "value": "oxandrolone" }, { "value": "oxymesterone" }, { "value": "oxymetholone" }, { "value": "prasterone", "expanded": "prasterone (dehydroepiandrosterone, dhea, 3β-hydroxyandrost-5-en-17-one)" }, { "value": "prostanozol", "expanded": "prostanozol (17β-[(tetrahydropyran-2-yl) oxy]-1’h-pyrazolo[3,4:2,3]-5α-androstane)" }, { "value": "quinbolone" }, { "value": "stanozolol" }, { "value": "stenbolone" }, { "value": "testosterone" }, { "value": "tetrahydrogestrinone", "expanded": "tetrahydrogestrinone (17-hydroxy-18a- homo-19-nor-17α-pregna-4,9,11-trien-3- one)" }, { "value": "tibolone" }, { "value": "trenbolone", "expanded": "trenbolone (17β-hydroxyestr-4,9,11-trien-3-one) and other substances with a similar chemical structure or similar biological effect(s)." }, { "value": "clenbuterol" }, { "value": "osilodrostat" }, { "value": "ractopamine" }, { "value": "selective androgen receptor modulators", "expanded": "selective androgen receptor modulators [sarms, e.g. andarine, enobosarm (ostarine), lgd-4033 (ligandrol), rad140, s-23 and yk-11]" }, { "value": "zeranol" }, { "value": "zilpaterol" } ] }, { "predicate": "peptide hormones, growth factors, related substances and mimetics", "entry": [ { "value": "darbepoetins", "expanded": "darbepoetins (depo)" }, { "value": "erythropoietins", "expanded": "erythropoietins (epo)" }, { "value": "epo-based constructs", "expanded": "epo-based constructs [e.g. epo-fc, methoxy polyethylene glycol-epoetin beta (cera)]" }, { "value": "epo-mimetic agents", "expanded": "epo-mimetic agents and their constructs (e.g. cnto-530, peginesatide)" }, { "value": "cobalt" }, { "value": "daprodustat", "expanded": "daprodustat (gsk1278863)" }, { "value": "iox2" }, { "value": "molidustat", "expanded": "molidustat (bay 85-3934)" }, { "value": "roxadustat", "expanded": "roxadustat (fg-4592)" }, { "value": "vadadustat", "expanded": "vadadustat (akb-6548)" }, { "value": "xenon" }, { "value": "k-11706" }, { "value": "luspatercept" }, { "value": "sotatercept" }, { "value": "asialo epo" }, { "value": "carbamylated epo", "expanded": "carbamylated epo (cepo)" }, { "value": "buserelin" }, { "value": "deslorelin" }, { "value": "gonadorelin" }, { "value": "goserelin" }, { "value": "leuprorelin" }, { "value": "nafarelin" }, { "value": "triptorelin" }, { "value": "corticorelin" }, { "value": "growth hormone analogues, e.g. lonapegsomatropin, somapacitan and somatrogon" }, { "value": "growth hormone fragments, e.g. aod-9604 and hgh 176-191" }, { "value": "growth hormone-releasing hormone", "expanded": "growth hormone-releasing hormone (ghrh) and its analogues (e.g. cjc-1293, cjc-1295, sermorelin and tesamorelin)" }, { "value": "growth hormone secretagogues", "expanded": "growth hormone secretagogues (ghs) and their mimetics [e.g. lenomorelin (ghrelin), anamorelin, ipamorelin, macimorelin and tabimorelin]" }, { "value": "gh-releasing peptides", "expanded": "gh-releasing peptides (ghrps) [e.g. alexamorelin, ghrp-1, ghrp-2 (pralmorelin), ghrp-3, ghrp-4, ghrp-5, ghrp-6, and examorelin (hexarelin)]" }, { "value": "fibroblast growth factors", "expanded": "fibroblast growth factors (fgfs)" }, { "value": "hepatocyte growth factor", "expanded": "hepatocyte growth factor (hgf)" }, { "value": "insulin-like growth factor 1", "expanded": "insulin-like growth factor 1 (igf-1) and its analogues" }, { "value": "mechano growth factors", "expanded": "mechano growth factors (mgfs)" }, { "value": "platelet-derived growth factor", "expanded": "platelet-derived growth factor (pdgf)" }, { "value": "thymosin-β4 and its derivatives e.g. tb-500" }, { "value": "vascular endothelial growth factor", "expanded": "vascular endothelial growth factor (vegf) and other growth factors or growth factor modulators affecting muscle, tendon or ligament protein synthesis/degradation, vascularisation, energy utilization, regenerative capacity or fibre type switching." } ] }, { "predicate": "beta-2 agonists", "entry": [ { "value": "arformoterol" }, { "value": "fenoterol" }, { "value": "formoterol" }, { "value": "higenamine" }, { "value": "indacaterol" }, { "value": "levosalbutamol" }, { "value": "olodaterol" }, { "value": "procaterol" }, { "value": "reproterol" }, { "value": "salbutamol" }, { "value": "salmeterol" }, { "value": "terbutaline" }, { "value": "tretoquinol", "expanded": "tretoquinol (trimetoquinol)" }, { "value": "tulobuterol" }, { "value": "vilanterol" }, { "value": "salbutamol", "expanded": "inhaled salbutamol: maximum 1600 micrograms over 24 hours in divided doses not to exceed 600 micrograms over 8 hours starting from any dose" }, { "value": "formoterol", "expanded": "inhaled formoterol: maximum delivered dose of 54 micrograms over 24 hours" }, { "value": "salmeterol", "expanded": "inhaled salmeterol: maximum 200 micrograms over 24 hours" }, { "value": "vilanterol", "expanded": "inhaled vilanterol: maximum 25 micrograms over 24 hours" } ] }, { "predicate": "hormone and metabolic modulators", "entry": [ { "value": "2-androstenol", "expanded": "2-androstenol  (5α-androst-2-en-17-ol)" }, { "value": "2-androstenone", "expanded": "2-androstenone (5α-androst-2-en-17-one)" }, { "value": "3-androstenol", "expanded": "3-androstenol  (5α-androst-3-en-17-ol)" }, { "value": "3-androstenone", "expanded": "3-androstenone (5α-androst-3-en-17-one)" }, { "value": "4-androstene-3,6,17 trione", "expanded": "4-androstene-3,6,17 trione (6-oxo)" }, { "value": "aminoglutethimide" }, { "value": "anastrozole" }, { "value": "androsta-1,4,6-triene-3,17-dione", "expanded": "androsta-1,4,6-triene-3,17-dione (androstatrienedione)" }, { "value": "androsta-3,5-diene-7,17-dione", "expanded": "androsta-3,5-diene-7,17-dione (arimistane)" }, { "value": "exemestane" }, { "value": "formestane" }, { "value": "letrozole" }, { "value": "testolactone" }, { "value": "bazedoxifene" }, { "value": "clomifene" }, { "value": "cyclofenil" }, { "value": "fulvestrant" }, { "value": "ospemifene" }, { "value": "raloxifene" }, { "value": "tamoxifen" }, { "value": "toremifene" }, { "value": "activin a-neutralizing antibodies" }, { "value": "activin receptor iib competitors", "expanded": "activin receptor iib competitors such as: decoy activin receptors (e.g. ace-031)" }, { "value": "decoy activin receptors", "expanded": "decoy activin receptors (e.g. ace-031)" }, { "value": "anti-activin receptor iib antibodies", "expanded": "anti-activin receptor iib antibodies (e.g. bimagrumab)" }, { "value": "myostatin inhibitors", "expanded": "myostatin inhibitors such as: agents reducing or ablating myostatin expression myostatin-binding proteins (e.g. follistatin, myostatin propeptide) myostatin- or precursor - neutralizing  antibodies (e.g. apitegromab, domagrozumab, landogrozumab, stamulumab)" }, { "value": "agents reducing or ablating myostatin expression" }, { "value": "myostatin-binding proteins", "expanded": "myostatin-binding proteins (e.g. follistatin, myostatin propeptide)" }, { "value": "myostatini - or precursor - neutralizing  antibodies", "expanded": "myostatin - or precursor - neutralizing  antibodies (e.g. apitegromab, domagrozumab, landogrozumab, stamulumab)" } ] }, { "predicate": "diuretics and masking agents", "entry": [ { "value": "desmopressin" }, { "value": "probenecid" }, { "value": "plasma expanders", "expanded": "plasma expanders, e.g. intravenous administration of albumin, dextran, hydroxyethyl starch and mannitol." }, { "value": "acetazolamide" }, { "value": "amiloride" }, { "value": "bumetanide" }, { "value": "canrenone" }, { "value": "chlortalidone" }, { "value": "etacrynic acid" }, { "value": "furosemide" }, { "value": "indapamide" }, { "value": "metolazone" }, { "value": "spironolactone" }, { "value": "thiazides", "expanded": "thiazides, e.g. bendroflumethiazide, chlorothiazide and hydrochlorothiazide" }, { "value": "torasemide" }, { "value": "triamterene" }, { "value": "vaptans" }, { "value": "vaptans, e.g. tolvaptan." }, { "value": "drospirenone" }, { "value": "pamabrom" }, { "value": "carbonic anhydrase inhibitors", "expanded": "topical ophthalmic administration of carbonic anhydrase inhibitors (e.g. dorzolamide, brinzolamide)" }, { "value": "felypressin", "expanded": "local administration of felypressin in dental anaesthesia" } ] }, { "predicate": "stimulants", "entry": [ { "value": "adrafinil" }, { "value": "amfepramone" }, { "value": "amfetamine" }, { "value": "amfetaminil" }, { "value": "amiphenazole" }, { "value": "benfluorex" }, { "value": "benzylpiperazine" }, { "value": "bromantan" }, { "value": "clobenzorex" }, { "value": "cocaine" }, { "value": "cropropamide" }, { "value": "crotetamide" }, { "value": "fencamine" }, { "value": "fenetylline" }, { "value": "fenfluramine" }, { "value": "fenproporex" }, { "value": "fonturacetam", "expanded": "fonturacetam [4-phenylpiracetam (carphedon)]" }, { "value": "furfenorex" }, { "value": "lisdexamfetamine" }, { "value": "mefenorex" }, { "value": "mephentermine" }, { "value": "mesocarb" }, { "value": "metamfetamine", "expanded": "metamfetamine(d-)" }, { "value": "p-methylamfetamine" }, { "value": "modafinil" }, { "value": "norfenfluramine" }, { "value": "phendimetrazine" }, { "value": "phentermine" }, { "value": "prenylamine" }, { "value": "prolintane" }, { "value": "3-methylhexan-2-amine", "expanded": "3-methylhexan-2-amine (1,2-dimethylpentylamine)" }, { "value": "4-fluoromethylphenidate" }, { "value": "4-methylhexan-2-amine", "expanded": "4-methylhexan-2-amine (methylhexaneamine, 1,3-dimethylamylamine, 1,3 dmaa)" }, { "value": "4-methylpentan-2-amine", "expanded": "4-methylpentan-2-amine (1,3-dimethylbutylamine)" }, { "value": "5-methylhexan-2-amine", "expanded": "5-methylhexan-2-amine (1,4-dimethylpentylamine, 1,4-dimethylamylamine, 1,4-dmaa)" }, { "value": "benzfetamine" }, { "value": "cathine**" }, { "value": "cathinone and its analogues", "expanded": "cathinone and its analogues, e.g. mephedrone, methedrone, and α - pyrrolidinovalerophenone" }, { "value": "dimetamfetamine", "expanded": "dimetamfetamine (dimethylamphetamine)" }, { "value": "ephedrine***" }, { "value": "epinephrine****", "expanded": "epinephrine**** (adrenaline)" }, { "value": "etamivan" }, { "value": "ethylphenidate" }, { "value": "etilamfetamine" }, { "value": "etilefrine" }, { "value": "famprofazone" }, { "value": "fenbutrazate" }, { "value": "fencamfamin" }, { "value": "heptaminol" }, { "value": "hydrafinil", "expanded": "hydrafinil (fluorenol)" }, { "value": "hydroxyamfetamine", "expanded": "hydroxyamfetamine (parahydroxyamphetamine)" }, { "value": "isometheptene" }, { "value": "levmetamfetamine" }, { "value": "meclofenoxate" }, { "value": "methylenedioxymetham- phetamine" }, { "value": "methylephedrine***" }, { "value": "methylnaphthidate", "expanded": "methylnaphthidate [((±)-methyl-2-(naphthalen-2-yl)-2-(piperidin-2-yl)acetate]" }, { "value": "methylphenidate" }, { "value": "nikethamide" }, { "value": "norfenefrine" }, { "value": "octodrine", "expanded": "octodrine (1,5-dimethylhex- ylamine)" }, { "value": "octopamine" }, { "value": "oxilofrine", "expanded": "oxilofrine (methylsynephrine)" }, { "value": "pemoline" }, { "value": "pentetrazol" }, { "value": "phenethylamine and its derivatives" }, { "value": "phenmetrazine" }, { "value": "phenpromethamine" }, { "value": "propylhexedrine" }, { "value": "pseudoephedrine*****" }, { "value": "selegiline" }, { "value": "sibutramine" }, { "value": "solriamfetol" }, { "value": "strychnine" }, { "value": "tenamfetamine", "expanded": "tenamfetamine (methylenedioxyamphet- amine)" }, { "value": "tuaminoheptane" }, { "value": "clonidine" }, { "value": "imidazole derivatives", "expanded": "imidazole derivatives for dermatological, nasal, ophthalmic or otic use (e.g. brimonidine, clonazoline, fenoxazoline, indanazoline, naphazoline, oxymetazoline, tetryzoline, xylometazoline) and those stimulants included in the 2023 monitoring program*" } ] }, { "predicate": "narcotics", "entry": [ { "value": "buprenorphine" }, { "value": "dextromoramide" }, { "value": "diamorphine", "expanded": "diamorphine (heroin)" }, { "value": "fentanyl", "expanded": "fentanyl and its derivatives" }, { "value": "hydromorphone" }, { "value": "methadone" }, { "value": "morphine" }, { "value": "nicomorphine" }, { "value": "oxycodone" }, { "value": "oxymorphone" }, { "value": "pentazocine" }, { "value": "pethidine" } ] }, { "predicate": "cannabinoids", "entry": [ { "value": "in cannabis", "expanded": "in cannabis (hashish, marijuana) and cannabis products" }, { "value": "synthetic cannabinoids that mimic the effects of thc" }, { "value": "natural and synthetic tetrahydrocannabinols", "expanded": "natural and synthetic tetrahydrocannabinols (thcs)" }, { "value": "cannabidiol" } ] }, { "predicate": "glucocorticoids", "entry": [ { "value": "beclometasone" }, { "value": "betamethasone" }, { "value": "budesonide" }, { "value": "ciclesonide" }, { "value": "cortisone" }, { "value": "deflazacort" }, { "value": "dexamethasone" }, { "value": "flucortolone" }, { "value": "flunisolide" }, { "value": "fluticasone" }, { "value": "hydrocortisone" }, { "value": "methylprednisolone" }, { "value": "mometasone" }, { "value": "prednisolone" }, { "value": "prednisone" }, { "value": "triamcinolone acetonide" } ] }, { "predicate": "beta-blockers", "entry": [ { "value": "acebutolol" }, { "value": "alprenolol" }, { "value": "atenolol" }, { "value": "betaxolol" }, { "value": "bisoprolol" }, { "value": "bunolol" }, { "value": "carteolol" }, { "value": "carvedilol" }, { "value": "celiprolol" }, { "value": "esmolol" }, { "value": "labetalol" }, { "value": "metipranolol" }, { "value": "metoprolol" }, { "value": "nadolol" }, { "value": "nebivolol" }, { "value": "oxprenolol" }, { "value": "pindolol" }, { "value": "propranolol" }, { "value": "sotalol" }, { "value": "timolol" } ] } ] }