diff --git a/changelog.d/7622.bugfix b/changelog.d/7622.bugfix
new file mode 100644
index 0000000000..bcb82f7b0b
--- /dev/null
+++ b/changelog.d/7622.bugfix
@@ -0,0 +1 @@
+Fix exceptions when fetching events from a remote host fails.
diff --git a/synapse/handlers/federation.py b/synapse/handlers/federation.py
index 75ec90d267..3e60774b33 100644
--- a/synapse/handlers/federation.py
+++ b/synapse/handlers/federation.py
@@ -501,7 +501,7 @@ class FederationHandler(BaseHandler):
                 min_depth=min_depth,
                 timeout=60000,
             )
-        except RequestSendFailed as e:
+        except (RequestSendFailed, HttpResponseException, NotRetryingDestination) as e:
             # We failed to get the missing events, but since we need to handle
             # the case of `get_missing_events` not returning the necessary
             # events anyway, it is safe to simply log the error and continue.