diff --git a/changelog.d/15570.misc b/changelog.d/15570.misc
new file mode 100644
index 0000000000..ee04509981
--- /dev/null
+++ b/changelog.d/15570.misc
@@ -0,0 +1 @@
+Allow `pip install` to use setuptools_rust 1.6.0 when building Synapse.
diff --git a/pyproject.toml b/pyproject.toml
index 640c6c4601..6bbc914af6 100644
--- a/pyproject.toml
+++ b/pyproject.toml
@@ -368,7 +368,7 @@ furo = ">=2022.12.7,<2024.0.0"
 # system changes.
 # We are happy to raise these upper bounds upon request,
 # provided we check that it's safe to do so (i.e. that CI passes).
-requires = ["poetry-core>=1.2.0,<=1.5.0", "setuptools_rust>=1.3,<=1.5.2"]
+requires = ["poetry-core>=1.2.0,<=1.5.0", "setuptools_rust>=1.3,<=1.6.0"]
 build-backend = "poetry.core.masonry.api"