diff --git a/changelog.d/3578.bugfix b/changelog.d/3578.bugfix
new file mode 100644
index 0000000000..9c52b6fa7e
--- /dev/null
+++ b/changelog.d/3578.bugfix
@@ -0,0 +1 @@
+Fix problem when playing media from Chrome using direct URL (thanks @remjey!)
diff --git a/synapse/rest/media/v1/download_resource.py b/synapse/rest/media/v1/download_resource.py
index ca90964d1d..f911b120b1 100644
--- a/synapse/rest/media/v1/download_resource.py
+++ b/synapse/rest/media/v1/download_resource.py
@@ -52,6 +52,7 @@ class DownloadResource(Resource):
             b" script-src 'none';"
             b" plugin-types application/pdf;"
             b" style-src 'unsafe-inline';"
+            b" media-src 'self';"
             b" object-src 'self';"
         )
         server_name, media_id, name = parse_media_id(request)