diff --git a/synapse/python_dependencies.py b/synapse/python_dependencies.py
index 0d8de600cf..c779f69fa0 100644
--- a/synapse/python_dependencies.py
+++ b/synapse/python_dependencies.py
@@ -58,7 +58,9 @@ REQUIREMENTS = {
     "phonenumbers>=8.2.0": ["phonenumbers"],
     "six": ["six"],
     "prometheus_client": ["prometheus_client"],
-    "attrs": ["attr"],
+
+    # we use attr.s(slots), which arrived in 16.0.0
+    "attrs>=16.0.0": ["attr>=16.0.0"],
     "netaddr>=0.7.18": ["netaddr"],
 }